IO University

    METASTATIC COLORECTAL CANCER

    Metastatic colorectal cancer (mCRC) can be managed with a variety of modalities, depending on individual patient factors. This module includes mCRC epidemiology, diagnosis, and staging. It provides an overview of different therapeutic approaches including surgery, chemotherapy, radiotherapy, and integrative approaches.

    Online modules have been approved for AMA PRA Category 1 Credit(s)™

    COMMERCIAL SUPPORT ACKNOWLEDGMENT

    This activity is supported by educational grants from Boston Scientific, BTG International Inc., Guerbet LLC, Healthtronics, and Teurmo Interventional Systems.

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    Management of Unresectable Colorectal Liver Metastases

    Upon completion of the activity, participants should be able to:

    • Describe standard chemotherapy regimens for unresectable colorectal carcinoma liver metastases (CLM)
    • Discuss clinical outcomes of systemic treatment for unresectable CLM
    • Define the role of Interventional Radiology (IR) locoregional therapies (LRTs) in treatment of unresectable CLM
    • Explain efficacy and safety outcomes of IR LRTs for unresectable CLM

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    Ablation vs Surgery

    Upon completion of the activity, participants should be able to:

    • Discuss the role of image guided ablation for the treatment of colon cancer liver metastases
    • Identify the subset of patients that are good candidates for image guided ablation with curative intent  
    • Evaluate the results of the current literature for ablation and compare them to surgery whenever applicable 

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    Diagnosis and Staging

    Upon completion of the activity, participants should be able to:

    • Use imaging to diagnose and stage metastatic liver disease in patients with colorectal cancer

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    Epidemiology

    Upon completion of the activity, participants should be able to:

    • Identify the age and gender specific incidence of CRC 
    • Describe the incidence of CRC based on tumor location
    • Evaluate the stage distribution of CRC at presentation

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    Integrating IO into the Treatment Paradigm

    Upon completion of the activity, participants should be able to:

    • Discuss the role of image guided ablation for the treatment of colon cancer liver metastases
    • Identify the subset of patients that are good candidates for image guided ablation with curative intent 
    • Evaluate the results of the current literature for ablation and compare them to surgery whenever applicable

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    Standard of Care Treatment - Chemotherapy

    Upon completion of the activity, participants should be able to:

    • Discuss medical management of patients with liver metastases of CRC 
    • Coordinate medical treatment with other approaches for patients with mCRC
    • Apply guideline recommendations to the management of patients with mCRC

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    Standard of Care Treatment - Surgery

    Upon completion of the activity, participants should be able to:

    • Discuss the current surgical techniques and possibilities of liver surgery 
    • Describe the limits of surgery, complications, and recurrence rate


    Please reference the Resource Guide: Metastatic Colorectal Cancer as a resource for all six (6) individual modules.

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